The Black Stars trainer has left out several key players for the international friendly against Cape Verde in Lisbon, Portugal on Wednesday.
Goalkeeper Adam Kwarasey, Emmanuel Agyemang-Badu, Kwadwo Asamoah, John Boye, Isaac Vorsah as well as Ayew brothers Andre and Jordan have been omitted from the squad that will take on the Blue Sharks.
Captain Asamoah Gyan has been excused for the game after he lost his mother last week.
The former Ghana captain is in the final phase of naming his final squad for the continental showpiece and has therefore invited those on the fringes including shot-stopper Daniel Nii Adjei, Fatau Dauda, Nana Kwesi Asare, Richmond Boakye-Yiadom, Richard Kissi Boateng, Derek Boateng, Samuel Inkoom and Albert Adomah to impress.
There are also debut call-ups for Inter Milan whizkid Joseph Alfred Duncan as well as in-form Maritiburg United defender Awal Mohammed and South African-based Edwin Gyimah.
It is widely believed those left out are sure candidates to make the final cut for the Nations Cup in South Africa but coach Appiah insists no-one has an automatic place in his final 23-man squad.
â€˜It is not whether someone is going to the Cup of Nations or not. There are some players that I need to take final decisions on,â€ Appiah said
â€œAs to those not called are guaraanted places in the team is not correct. Everyone has got a chance to go.
â€œThe important thing is to look at those who are really commited to fight for Ghana. I will be looking at disciplinary aspect as well.
â€œI believe anyone chosen to play in either friendly or competitive match must prove their worth so that I can make the right decision.â€
The Black Stars are housed in group B where they will take on old foes DR Congo, Mali and Niger in Port Elizabeth.
Ghana will be looking to end a 31-year-wait for an African crown in South Africa.